Two positions for early-stage researchers (ESR) in tissue engineering/ultrafast laser micro- nanostructuring, Laboratory of Micro and Nano photonics, Sofia, Bulgaria

The Femtoscience application group – Institute of Electronics -Bulgarian Academy of Sciences-  is a Beneficiary among 12 other organizations with a leading coordinator from the University of Birmingham in  H2020 ITN Marie Curie project: Antimicrobial Integrated Methodologies for orthopedic applications – AIMed has two positions for early-stage researchers (ESR).

The deadline for application is: 31.08.2020
The job starts from: 01.10.2020
Contact: Albena Daskalova albdaskalova@gmail.com

ESR12: Ultra-short laser surface modification of polymers, bioceramics and metals for enhancement of biological and antimicrobial properties

Objectives: (i) Employment of ultra-short laser-assisted processing to obtain highly-ordered porous arrays network diverse and patterning designs on ultra-high molecular weight polyethylene surface, ceramics (CaP, Hydroxyapatite (HAp), and Zr) and biocompatible metal surfaces (Titanium alloys (Ti-6AL-4V); (ii) optimization of biomimetic surface properties and functionalization via laser texturing. Development of diverse patterning designs by employing various optical techniques (pulse shaping, laser-induced periodic surface structuring (LIPSS)); (iii) Obtaining a hierarchical porosity via the creation of micro- and nano-structuring utilizing laser-based surface modification and LIPSS formation; (iv) Complete characterization and analysis via a set of analytical methods (SEM, AFM, XRD, FTIR, XPS, Wettability studies) of the designed structures and interface layers processed via Ultra-Fast Laser techniques to obtain surfaces with enhanced structural, biological and antimicrobial performance; (v) Examination of chemical properties and wear resistance of obtained samples before and after laser treatment for evaluating the best condition of materials processing and creation of an implant with enhanced biological and mechanical properties.

Expected Results: (i) Fabrication of polymer, bioceramics and metal substrates and porous scaffolds; (ii) Obtaining diverse patterning designs via laser surface texturing and laser-induced periodic surface structures (LIPSS); (iii) Evaluating the best conditions for material treatment via parametric study of the laser-material interaction process; (iv) Characterisation of fabricated scaffolds and modified surfaces (SEM, AFM, confocal microscopy, Computer tomography, XRD, FTIR, wettability studies); (v) Modelling the process of laser-materials interaction; (vi) In vitro study of the designed scaffolds (cytotoxicity and cellular growth and differentiation); (vii) Antimicrobial assays; (viii) Ph.D. Thesis

 

ESR13: Development and characterization of textured polymer/ceramic composites by ultra-short laser surface treatment

Objectives: (i) To develop textured bioceramic (ZrO2, HA) -biodegradable polymer (PLLA) composites; (ii) Surface functionalization of ceramics and composites by ultra-short laser-based modification methods; To characterize the mechanical, morphological and topographical properties as well as the effect of laser treatment on cells and bacteria response.

Expected Results: (i) Optimisation of process parameters for bulk model ceramics; (ii) Formation of spherical interconnected macroporous ceramics produced by slurry impregnation of an organic bead skeleton; (iii) Formation of tubular macroporous structures obtained by freeze casting; (iv) Additively manufactured complex structures produced by stereolithography; (v) Polymer composites will be developed by PLLA infiltration of the macroporous structures developed above; (vi) Structural and physicochemical characterizations of all developed structures above by scanning electron microscopy focused ion beam, confocal microscopy, 3D microscopy, atomic force microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, Raman spectroscopy, and contact angle measurements; (vii) Mechanical properties of all developed materials; (viii) Evaluation of cellular response to designed surface models; (ix) Antimicrobial and biocompatibility evaluation; (x) Ph.D. thesis