Access Facilities - CUSBO

CUSBO Centre for Ultrafast Science and Biomedical Optics, Politecnico di Milano, Milan, Italy

Access to ultra-fast laser facilities and physics and biology research.

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Contact: Sandro Desilvestri Email

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The Centre for Ultrafast Science and Biomedical Optics is a large facility in Italy within the field of lasers, optics and spectroscopy. Research is performed on ultrafast lasers, non-linear optics, high-intensity laser-matter interactions, ultrafast processes in quantum confined materials, non-invasive optical characterisation of biological tissues, broad band fluorescence lifetime spectroscopy and imaging of diffusive media.

Activities:

Few optical cycle laser sources offer the possibility to foresee experiments with an extremely high time resolution in the fields of molecular dynamics, formation and breaking of chemical bonds in chemistry, ultrafast charge and energy transfer.

Other important areas are ultrafast processes in materials for light energy conversion, biological photoreceptors and quantum confined systems. Time-resolved diffuse reflectance and transmittance spectroscopy system opens the way to a new set of basic researches where both absorption and scattering spectra are correlated to physiological or pathological states of tissues.

Systems, producing 2D maps of fluorescence decays, can be used for in vivo pharmacokinetics studies, non-invasive diagnosis of superficial tumour, and in vitro study of cells.

Research opportunities within the Laserlab access activity:

The main working stations provided by the infrastructure are:

30 fs pulses, from amplified Ti:sapphire system, with 0.8 mJ energy at 1 kHz
Sub-10 fs pulses at 0.3 mJ energy at 1 kHz repetition rate
Sub-10 fs pulses tunable in the visible (500-700 nm), generated by ultra-broadband parametric amplification
Extreme UV and soft x ray coherent light source (sub-10 fs duration) based on high order harmonic generation
Sub-100 fs pulses in near-infrared (1.2-1.5 mm) at 1 kHz by parametric amplification
Fully automated, continuously tunable VIS to NIR ps sources at high repetition rate (80 MHz)
Time -resolved spatial, spectral- and temporal- mapping of the optical properties in biological tissues
ps fluorescence lifetime imaging of biological media
Femtosecond laser micro -machining set-up

Set-up for high energy few optical cycle pulses

lab-cusbo

All working stations are equipped with measurement apparatus: as, in particular, systems such as pump -probe, three pulse scattering, fluorescence up-conversion, fluorescence lifetime imaging, photon migration spectroscopy and imaging. To complement the offer to potential users, working stations with more conventional laser systems are also available.

Access Facilities - CUSBO

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